Gramocef-O 400 mg is an antibiotic medication containing Cefixime as its active ingredient. Cefixime is a third-generation cephalosporin antibiotic, which is effective against a broad range of bacterial infections.
Composition:
- Cefixime (400 mg): A broad-spectrum cephalosporin antibiotic that is effective against both gram-positive and gram-negative bacteria.
Mechanism of Action:
- Cefixime works by inhibiting the synthesis of the bacterial cell wall, which ultimately leads to cell lysis and death. It binds to specific penicillin-binding proteins (PBPs) inside the bacterial cell wall, inhibiting the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, which is essential for bacterial growth and stability.
Indications:
Gramocef-O 400 mg is used to treat various bacterial infections, including:
- Respiratory tract infections such as bronchitis and pneumonia.
- Urinary tract infections (UTIs).
- Otitis media (middle ear infections).
- Pharyngitis and tonsillitis.
- Gonorrhea (uncomplicated).
- Acute bacterial sinusitis.
Dosage and Administration:
- The typical adult dose is one 400 mg tablet taken once daily or 200 mg taken twice daily. The duration of treatment usually ranges from 5 to 14 days, depending on the type and severity of the infection.
- The tablet should be taken with or without food.
- It is important to complete the entire course of therapy, even if symptoms improve before finishing the medication, to prevent the development of antibiotic resistance.